Abstract: "Geological interface" is the boundary of various geological units in the earth's crust. It clarifies the contact relationship between geological bodies, and usually also a geological space where the deposit is formed."Metallogenic interface" refers to the place where mineralization occurs and geological interface with the deposit."Marginal metallogenesis" clarifies the occurrence of mineralization at the metallogenic interface and its evolution process, ore-forming material enrichment and post-mineralization preservation process. According to the differences in geological and metallogenic processes, the metallogenic interface can be divided into 9 groups. Metallogenic interfaces are the most easily recognizable and direct indications for prospecting, and constitute one of the theoretical bases of scientific prospecting, and summarize the law of mineralization.