Abstract: The utilization of underground space has become a major means of solving the problems plaguing cities, and the precise exploration of underground space is fundamental to its development and utilization. However, the theories, method combination, elements to be acquired and data application regarding the exploration of urban underground space with strong interference are yet to be determined in a united manner. The all-element dataset of combined exploration of urban underground space with strong interference (also referred to as the Dataset) relies on these four projects initiated by the China Geological Survey: Risk Assessment of Geologic Disasters in Important Towns in Shaanxi Province (2013—2016), Comprehensive Geological Survey in Guanzhong – Tianshui Economic Region (2016—2018), Multi-element Urban Geological Survey in Xi’an (2018—2021) and Comprehensive Geological Survey in Yan’an, a Former Base of the Communist Party of China (2018—2021). The aim of these projects were to meet the demand for quality assessment of rock and soil masses and also the assessment, development and utilization of urban underground space. During the development of the Dataset, monitoring-while-drilling (MWD) technology was introduced based on regular geophysical prospecting, drilling and testing. Furthermore, a total of 13 parameters was logged, a combined method of underground space exploration was established and the all-element data required for quality assessment of rock and soil masses and urban underground space were obtained. The data in the Dataset were obtained from the urban area of Shanyang County, in the Qinba Mountains of Shaanxi Province, the urban area of Xi’an City in the Guangzhong Basin and the urban area of Yan’an City in the Loess Plateau. It consists of five types of data, i.e., engineering geological drilling, testing, multi-parameter logging, MWD and ground geophysical prospecting. In detail, the data were acquired from 144 engineering geological boreholes, 672 testing samples, 111 boreholes for the logging of 13 parameters by geophysical prospecting, 36 MWD boreholes and 5 profiles of ground geophysical prospecting obtained via 4 methods. In total, the Dataset consists of 968 sets of data and 3 664 files in the formats of .jpg, .xls, .doc, .mpj and .dwg. It can be applied to the quality assessment of rock and soil masses, the establishment of 3D urban geological all-element models, the assessment of underground space resources, the research on the coupling relationship between the quality and physical properties of rock and soil masses and the scientific research of urban geology.