Abstract: Nanling Scientific Drilling-1(NLSD-1) is the deepest drilling engineering in South China ore concentration. The total drilling depth is 2967.83 m. 120 gold, silver, lead and zinc, bismuth, tungsten and uranium mineralization spots were exposed. Mineralization can be divided into fracture zone, siliceous vein type, quartz-feldspar vein type, which are produced in such forms as tracing detected very favorable industrial orebody potential. Vertical element mineralization regularity exhibits gold-silver-copper combination and lead-zinc combination. Bismuth anomaly is correlated significantly with the thiophile element mineralization. Precious metal mineralization anomalies are concentrated in nappe, whereas tungsten, tin and uranium mineralization tends to increase toward the depth, with both having specialization in lithological strata, tectonics and magmatic rocks in the borehole. According to uncovered information of vertical mineralization regularity revealed by NLSD-1 in combination with regional metallogenic regularity, the authors propose four prospecting directions:(1)V10-V31 in the nappe that extends to the east and to the depth; (2)Tungsten-tin polymetallic mineralization under the nappe; (3)Three deep spatial positions where thick orebodies may occur; (4)Porphyry-explosion breccia type mineralization in the periphery of Gaoshanjiao Hill-Bijia Hill.